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Antibiotics Webinar | Mobile Elements and Antibiotic Resistance

25 May 2021, 15:00

Antibiotics, Mobilization Events, Defence/counter-defence Systems, Antibiotic Resistance Evolution, Mobile Genetic Elements
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Webinar Information

2nd Antibiotics Webinar

Mobile Elements and Antibiotic Resistance

The inappropriate use of antibiotics has promoted the rise in antibiotic resistance in bacteria. Resistance evolution is often mediated by horizontal gene transfer events. This webinar will provide the latest perspectives on the mobilization events and defence/counter-defence systems involved in antibiotic resistance evolution. The panel of scholars includes Daria Van Tyne from the University of Pittsburgh School of Medicine, Rachel Wheatley from the University of Oxford, and Adam Roberts from Liverpool School of Tropical Medicine. The webinar is suitable for everyone interested in furthering their understanding of the role of mobile genetic elements on antibiotic resistance evolution.

Dr. João Botelho
Max Planck Institute for Evolutionary Biology, Ploen, Germany
Evolutionary Ecology and Genetics, CAU Kiel, Kiel, Germany

Date: 25 May 2021

Time: 3:00pm CEST

Webinar ID: 915 0017 1687

Webinar Secretariat: antibiotics.webinar@mdpi.com

Chair: Dr. João Botelho

The following experts will present and talk:

Dr. João Botelho, Max Planck Institute for Evolutionary Biology, Germany

João Botelho is a Postdoctoral Research Associate in Antimicrobial Resistance Evolution at the Max Planck Institute for Evolutionary Biology in Germany. His research is focused on the crossroads of mobile genetic elements and antibiotic resistance. João completed his PhD in 2018 at the University of Porto in Portugal, in which he was using experimental and computational approaches to study mobilization events of antimicrobial resistance genes in Pseudomonas aeruginosa.

Dr. Rachel Wheatley, University of Oxford, UK

Rachel Wheatley is a Postdoctoral Research Associate in Bacterial Evolution at the University of Oxford. Her research is focused on understanding the genomic drivers of antibiotic resistance in Pseudomonas aeruginosa, and factors influencing the evolution of this pathogen more broadly. Rachel completed her PhD in 2019 also in Oxford, in which she was using functional genomics approaches to understand bacterial metabolism.

Dr. Adam Roberts, Liverpool School of Tropical Medicine (LSTM), UK

Adam Roberts graduated in Applied Biology from Coventry University in 1995 and with a PhD in the molecular microbiology of transferable AMR from the University of London in 2002. Adam worked as a Post-Doctoral Research Fellow, Lecturer and Senior Lecturer at University College London until joining LSTM in February 2017 where he leads on AMR research. His research activities focus on the emergence and spread of antimicrobial resistance amongst bacteria, the characterisation of mobile genetic elements responsible for this transfer and the development of new drugs in order to treat infections. He is an advisor to the Longitude Prize and the Royal Society of Tropical Medicine and Hygiene, runs The Transposon Registry and recently co-ordinated the JPIAMR funded Network of European and African Researchers on AMR (NEAR-AMR).

Dr. Daria Van Tyne, University of Pittsburgh, PA, United States

Daria Van Tyne is an Assistant Professor in the Division of Infectious Diseases at the University of Pittsburgh School of Medicine. She completed her PhD at the Harvard T.H. Chan School of Public Health in the lab of Dyann Wirth, followed by a post-doc in the lab of Mike Gilmore at Harvard Medical School. Daria started her research group at the University of Pittsburgh in the summer of 2018. The Van Tyne lab studies how bacteria evolve resistance to antibiotics and host immune defences, using comparative genomics and functional analysis.


Program

Speaker/Presentation

Time in CEST

Dr. João Botelho

Chair Introduction

3:00 – 3:05 pm

Dr. Rachel Wheatley

CRISPR-Cas Systems and Horizontal Gene Transfer In Pseudomonas Aeruginosa

3:05 – 3:35 pm

Dr. Adam Roberts

Functional Assay Development to Detect Mobile Genetic Elements From Metagenomes and Their Mobility Within Bacterial Cells

3:35 – 4:05 pm

Dr. Daria Van Tyne

Horizontal Transfer Of Mobile Genetic Elements Among Hospital-Associated Bacteria

4:05 – 4:35 pm

Q&A Session

4:35 – 4:55 pm

Closing of Webinar
Dr. João Botelho

4:55 – 5:00 pm

Webinar Content

On Tuesday, 25 May 2021, MDPI and the Journal Antibiotics organized the second webinar on Antibiotics, entitled "Mobile Elements and Antibiotic Resistance".

The chair of the session, Dr. João Botelho, from Max Planck Institute for Evolutionary Biology in Germany, made an introduction on the topic and was the responsible of presenting the panel of speakers of the webinar.

The session started with a Dr. Rachel Wheatley's talk on how the CRISPR-Cas Systems could aid in Horizontal Gene Transfer (HGT) events in bacteria, specially focused on Pseudomonas Aeruginosa.

Our second speaker, Dr. Adam Roberts, gave a speech on the development of a Functional Assay to Detect Mobile Genetic Elements From Metagenomes and how those mobile elements can move within Bacterial Cells.

Finally, Dr. Daria Van Tyne, contextualized those HGT events within Hospital-Associated Bacteria, a place known to be populated by super-bugs carrying several resistance genes.

The presentations were followed by a Q&A, moderated by the Chair. The webinar was offered via Zoom and required registration to attend. The full recording can be found here on Sciforum website. In order to stay updated on the next webinars on Antibiotics, be sure to sign up for our newsletter by clicking on “Subscribe” at the top of the page.

Registration

In order to attend the webinar, please register by clicking on the button below.


This is a FREE webinar. The number of participants to the live session is limited but the recording will be made available on Sciforum shortly afterwards. Registrations with academic institutional email addresses will be prioritized. People can send in their questions by email to antibiotics.webinar@mdpi.com.

Relevant Special Issues

Mobile Elements and Antibiotic Resistance
Guest Editor: Dr. João Botelho
Deadline for manuscript submissions: 31 May 2021

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